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L11,12 , Pesticides, toxicology

Lecture Video

Questions

  1. Peak plasma cinc. Of OPS is:
    a-1 H
    b-6 H
    c-12 H
    d- 24 H

  2. Mechanism of action of OPS is:
    a-# release of Ach
    b-# synthesis of Ach
    c-# Ach esterase action
    d-# Ach re-uptake

  3. The most specific investigation for OPS :
    a- CBC
    b- muscle tone
    c- cholinesterase level
    d- urine analysis

  4. Cause of death in OPS tx:
    a- Heart failure
    b-respiratory arrest
    c- shock
    d-renal failure

  5. Therapeutic end point of atropine is:
    a-pupillary dilatation
    b-lung dryness
    c-seizures stopped

  6. All of the following considered mechanism of action of organic chlorides:
    a- interfering with repolarization
    b- impairing polarized state
    c- sensitize myocardium
    d- all of the above 


  1. All of the following considered mechanism of action pyrethroids:
    a- prolonged depolarization
    b-block nerve conduction
    c-block Cl- channels
    d- All of the above


  1.  Mechanism of action of rodenticides:
    a- block vit K synthesis
    b- block vit K absorption
    c- block vit K metabolism
    d- stimulate vit K synthesis


  1. “Cytochrome C oxidase inhibition” is a mechanism of action of:
    a-chloride
    b- OPS
    c-warfarin
    d-zinc phosphide


  1. Pyrethrum have systemic toxicity:
    a- True
    b- False


  1. OPS have no sympathetic manifestation:
    a- True
    b-False


  1. Aging means : OP-AchE bond become permanent after 12H :
    a- True
    b- False 


  1. Which of the following are highly toxic rodenticides:
    a-thalium
    b-strychnine
    c-arsenic.
    d- all of the above

14-All are features of muscarinic effects of OPC poisoning, except

  1. Mydriasis. Es

  1. Lacrimation.

  1. Bradycardia.

  1. Sweating.


15-In opc poisoning the following are indicated except:


  1. Decontamination


  1. Oximes


  1. Atropine


  1. Forced diuresis 



  1. b

  2. c

  3. c

  4. b

  5. b

  6. d

  7. d

  8. a

  9. d

  10. b( no systemic toxicity)

  11. b (have sympathetic manifestation)

  12. b (24-36 h)

  13. d

  14. A

  15. D

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