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Microbiology_L12, tolerance and autoimmune

 L12, tolerance and autoimmune 




MCQ

1- Tolerance is …..
A- immunity hyperactivity
B- immune unresponsiveness
C- Reaction leads to tissue damage
D- None of the above

2- Central T tolerance happens in which period of time ?
A- Childhood
B- Embryonic life
C- Adulthood
D- Old Age

3- Central B cell tolerance happens by
A- Negative selection
B- Change the receptors
C- Negative selection and change the receptors
D- Non of the above

4- Anergy happens due to…
A- Continuous stimulation to the immune cell
B- inhibition of immune cell by T reg cell
C- increase of the co-stimulation to the immune cell
D- Lack of co-stimulation to the immune cell

5- Complex molecule induce tolerance more than simple molecules
A- TRUE
B- FALSE

6- Cross reactivity terminates the tolerance
A- TRUE
B- FALSE

7- Which of the following is a mechanism of AID
A- Deletion
B- Anergy
C- sequestrated antigen release
D- All of the above

8- Rheumatoid arthritis is common with …
A- HLA DR3
B- HLA DR4
C- HLA DR5
D- HLA DR 3,4

9- Rheumatoid factor happens when ….
A- Ig M antibodies against Ig G
B- Ig G antibodies against IgM
C- Ig M antibodies against Ig A
D- Non of the above

10- Precipitation of Z band on the RBCs cause its destruction by
immunity, this is considerate …..
A- Harmful autoimmunity
B- Beneficial autoimmunity
C- Non of the above

11- Cytotoxic reactions ( Type II ) occurs in …..
A- Ulcerative colitis
B- SLE
C- RA
D- hemolytic anemia

12- Ulcerative colitis happens due to
A- Delayed type hypersensitivity
B- Immune complex deposition
E- Cytotoxic reaction
F- All of the above

13- Decreased complement indicates the probability of AID
A-TRUE
B- FALSE

14- Plasma exchange is not a method of management in AID case
A- TRUE
B- FALSE

Answers

1-B
2-B
3-C
4-D
5-B
6-A
7-C
8-B
9-A
10-B
11-D
12-A
13-A
14-B
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