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Para_Tut1_Immunity to parasitic infection

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Tut1, Immunity to parasitic infection


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Questions

Choose the correct answers:



1_Human can't work as a definitive host for all of the following except:

A.malaria

B.Toxoplasma

C.Bird Schistosomes


2_All of the following are genetic and nutritional factors to falciparum malaria except:

A.haemoglobinopathy

B.anemia

C.Duffy blood factor

D.G-6PD diffeciency


3_All of the following are genetic and nutritional factors to all malaria except:

A.anemia

B.age of RBCs

C.Duffy blood factor


4_All of the following are mechanisms of acquired specific immunity against parasites except:





A.production of specific IGE and eosinophilia

B.induction of granulomatous response and fibrosis

C.cytolytic T-lymphocytes activation

D.CD8+helper T-cell activation





5_Isosporiasis as a protozoa is unusual cause of:


A.eosinophilia

B.specific IgE antibody production

C.Both



6_Helminthes infection can cause:


A.production of specific IGE antibody

B.eosinophilia

C.Both


Schistosoma egg can induse:_7


A.granulomatous response

B.fibrosis

C.Both



Lymphatic filariasis results in:_8


A.fibrosis and granuloma

B.fibrosis without granuloma

C.granuloma without fibrosis


9_ r.......results in CD4+helper T-cell activation and cytokines production:


A.toxoplasma

B.filaria

C.leshmania

D.All of the above


10_ r.......results in cytolyticT-lymphocytes activation (CTLs)


A.malaria

B.protozoa

C.Both


All of the following is a type of _11 protective immune response except:


A.complete self cure

B.T-cell dependent pathology

C.solid immunity

D.premunition immunity


12_Cryptosporidiosis in immunocompetent host is an example of:


A.complete self cure

B.complete protection from reinfection (solid immunity)

C.premunition immunity



13_Immunocompetent patient of oxoplasmosis is an example of:


A.complete self cure

B.complete protection from reinfection

C.premunition immunity



All of the following are examples of_14 immunopathology of parasitic disease except:


A.immune complexes

B.Autoantibodies

C.T-cell dependent pathology

  D.premunition Immunity



All of the following is an example of_15 immunopathology due to production of immune complexes except:


A.Nephritis

B.Vasculitis

C.Eosinophilia

D.Lymphangitis


All of the following are examples of _16.  T-cell dependent pathology except:

A.Hepatic fibrosis and portal HTN

B.Lymphatic filariasis

C.Non of the above


………..is an example of immediate_17 hypersensitivity response:


A.calabar swelling

B.Larvae currens In strongyloidiasis

C.Tropical pulmonary eosinophilia

D.All of the above


………..is due to autoantibodies:_18


A.Chaga's disease

B.Onchocerciasis

C.Sleeping sickness

D.All of the above


19_Evasion of immune mechanisms by parasites include:


A.Hiding from immune system

B.Shedding of surface antigen

C.Antigen masking

D.All of the above

All of the following can hide from immune_20 system in intestinal lumen except:

A.Toxoplasma

B.Ascaris

C.Entrobius



All of the following can hide from immune_21 system in a cyst except


A.Hydatid

B.Ascaris

C.Trichinella


Coating with…………..is a way of_22 antigen masking:

A.ABO blood group

B.Glycolipids

C.MHC molecules

D.All of the above



…………….can hide from immune_23 system antigenic variation:


A.T-brucei

B.Toxoplasma

C.Malaria


_24…………… Can hide from immune system by shedding of its coat after skin penetration:


A.malaria


B.Schistosoma cercariae


C.T-brucei


25_In Microfilaria+Ve patient there is high level of IgG4 that leads to all of the following except:



A.Blocking of IgE-dependant allergic responses

B.formation of large immune complexes instead of small IC

C.formation of small immune complexes instead of large IC


Patients with progressive Kala Azar _26 fail to develop


A.delayed type hypersensitivity


B.immediate type hypersensitivity



Value of IMMUNODIAGNOSIS include:_27


A.useful for survey and screening studies

B.To monitor the course of infection

C.To evaluate how protected you are against parasites

D.All of the above





All of the following are true about_28 antibody detection assay except:


A.can't differentiate between species and subspecies

B.High cross reaction with other genera
 

C.More specific than antigen detection assay

D.More sensitive than antigen detection assay





Antibody detection assay can result in:_29


A.false negative

B.false positive


All of the following are true about_30 antigen detection assay except:


A.may result in false positive

B.more specific than antibody detection assay

C.more sensitive than antibody detection assay



Skin tests include:_31

A.Bachman test

B.Toxoplasmin test

C.Casoni test

D.All of the above





Treatment of occult filariasis include:_32


A.Ivermectin and DEC

B.Cosmotic or microvascular surgery

C.Both


Answers


1_ A
2_ C
3_ C
4_ D
5_ A
6_ C
7_ C
8_ B
9_ D
C_10
B_11
A_12
C_13
D_14
C_15
C_16
D_17
D_18
D_19
20_A
21_B
22_D
23_A
24_B
25_C
26_A
27_D
28_C
29_A
30_C
31_D
32_C
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