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MCQ

1- 2-year-old African-American child presents with painful swelling of the hands and feet. Laboratory evaluation reveals hemoglobin of 9 g/dL with white blood cell count of 11,500 and platelet count of 250,000. Which additional laboratory test will support your diagnosis?

(A) skeletal survey

(B) VDRL testing

(C) bone marrow aspiration

(D) hemoglobin electrophoresis

(E) serum calcium measurement

Answer D


2- An 18-month-old toddler has microcytic anemia. Which dietary history finding best explains this?

(A) pica

(B) lack of fresh vegetables in the diet

(C) intake of inadequate amounts of fruit juice

(D) intake of excessive amounts of vitamin C

(E) intake of large amounts of unmodified cow’s milk

Answer E


3-What hematologic abnormality should you suspect in a newborn with bilateral absence of radii?

(A) thrombocytopenia

(B) anemia

(C) neutropenia

(D) pancytopenia

(E) lymphopenia

Answer A


4-A7-year-old boy has abdominal pain and a rash that started several days ago. On examination,you notice a palpable purpuric rash over his calves and buttocks with swelling of both ankles. Abdominal examination is unremarkable. What is the most likely laboratory finding?

(A) decreased platelet count

(B) hypochromic microcytic anemia

(C) elevated blood urea nitrogen and creatinine

(D) low C3 complement levels

(E) normal clotting parameters

Answer E


5-An 18-month-old male toddler presents with pallor. He drinks 64 oz of cow milk per day. The examination is significant only for an obese and playful male with pallor. Stool is negative for blood. Which laboratory test would most likely reveal the diagnosis?

1.

(A) chest x-ray

(B) examination of stool for ova and parasites

(C) complete blood count

(D) serum haptoglobin

(E) bone marrow aspirate

Answer C

2. Testing reveals a mean corpuscular volume of 60 fL (nL 72–86 fL) and an elevated red cell distribution width. The most likely diagnosis is

(A) vitamin B12 deficiency

(B) B-cell leukemia

(C) hemosiderosis

(D) iron deficiency anemia

(E) sickle cell disease

Answer D


6-A 4-year-old male presents with a 1-day history of abdominal pain and vomiting. He is afebrile and has no diarrhea. He complains of knee pain bilaterally, and there is some tenderness of the knee joints but No effusions. Within 24 hours he develops a rash on his legs and buttocks which is petechial and Purpuric, and his platelet count is normal. What is the most likely diagnosis?

(A) hemolytic uremic syndrome

(B) Henoch-Schِ nlein purpura

(C) acute glomerulonephritis

(D) Kawasaki disease

(E) systemic lupus erythematosus

Answer B


7- 2years old child presented with multiple skin nodules, Proptosis, abdominal enlargment  US show abdominal mass  It’s most probably to be 

A- Neuroblastoma 

B- Wilm's tumor 

C- mesothelioma 

D- Hepatoblastoma 

E- Rhabdomyoma

Answer A


8- The following are causes of Microcytic anemia except 

A- lead poisoning 

B- Ankylostoma

C- Thalassemia 

D- marrow hypoplasia

E- Sidroblastic anemia 

Answer D


9- Splenectomy lead to clinical cure in the following anemia 

A- Sidroblastic anemia 

B- spherocytosis 

C- Sickle cell anemia 

D- G6PD Deficiency anemia 

E- Alpha Thalassemia 

Answer B


10- priapism occur in 

A- Beta Thalassemia 

B- Alpha Thalassemia 

C- Sickle cell anemia 

D- Congenital spherocytosis 

E- Autoimmune hemolytic anemia 

Answer C


11- Low platelet count with increase PT and PTT 

A-Evan syndrome 

B- DIC

C- Von willebrand disease 

D- Hemolytic uremic syndrome 

E- Henoch schonlien purpura 

Answer B


12- Hemophilia C due to 

A- factor Vlll Deficiency 

B- factor lX Deficiency 

C- factor X Deficiency 

D- factor Xl Deficiency 

E- factor Xll Deficiency 

Answer D 


13- 3yaers old child presented with abdominal mass and Microcytic Hematuria 

A- Hidgkin disease 

B- Ewing sarcoma 

C- Wilm's tumor 

D- Renal cell carcinoma 

E- Rhabdomyoma 

Answer C


14- The following drug may cause Megaloblastic anemia 

A- phenytoin 

B- sulfa

C- penicillin 

D- Aspirin 

E- Nitrofurantoin 

Answer A


15- Hypersplenism characterized by the following except 

A- Splenomegaly 

B- Pancytopenia 

C- hypocellular Bone marrow 

D- improved by Splenectomy 

E- occur in Portal Hypertension

Answer C


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