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Pharma-L2 , Anticoagulants

 

Lecture Video




Short Essay

1. ClassificationofAnticoagulants……………. …..,……………..,……………….
2. Oral preparation ………,………………,……..
3. Paranteral preparation …….,………..,…….
4. Disadvantage of oral anticoagulants….
5. Advantage of Rivaroxaban…………………….
6. Mechanism of Ancorod……………………
7. Uses of Heparin as prophylaxis……………………….
8. Antidote of Warfarin …………………….
9. Main side effect of Heparin ……………………….
10. Drug increase anticoagulants effect ……………

Choose the most correct Answer

1.Diminshed ionized calcium used in …..
( Bloood Banks – Blood samples- Both )
2.Drug use in Treatment of AF ……
( warfarin – Apixaban – Dabigatran )
3.Renal impairment is the most side effect
( Wafarin – Apixaban – Dabigatran)
4. Low Molecular weight Heparin is ......
(Tinzaparin - wafarin - Heparin)
5. The most best drug used in treatment of venous thromboembolism as prophylaxis ...............
(Fondaparinux - Ancorod - Dabigatran)
6. Drugs of direct thromboin inhibitor.....................
( Hirudin – lepirudin – Navilirudin – All)
7. Stimulate conversion of fibrinogen to abnormal fibrin…........
(Fondaparinux – Ancorod – Dabigatran)
8. Drug has a Teratogenic effect on Pregnant women
(Tinzaparin – wafarin – Heparin)
9. Protamine sulphate is antidote for………….
(Tinzaparin – wafarin – Heparin)
10.Drug descrease anticoagulants effect.......
(Allopurinol – cimetidine – Rifampicin)
11. Transient alopecia is main side effect of……
(Tinzaparin – wafarin – Heparin)
12. Drug is used to treat hyperlipidemia ………
(Tinzaparin - wafarin - Heparin)

True or False

1. Sodium oxalate is in Blood Banks (. )
2. Wafarin act as paranteral preparation of Anticoagulants (. )
3. Daltoparin is LMW Heparin(. )
4. Lepirudin bind to active site of thrombin (. )
5. Heparin is extract of Viper Venom . (. )
6. Warfarin is secreted in milk ( )
7. Heparin is mucopolysaccharides and carry electropositive charge. (. )
8. Warfarin can pass placenta and BBB (. )
9. Warfarin is Anticoagulants Vivo and Vitro. (. )
10. Phenobarbitone increase anticoagulants effect (……………)

Answers of the Question

Short assay


1. Substance remove ionic calcium, oral preparation ,parenteral preparation
2. Warfarin, Direct thromboin inhibitor, Direct factor Xa inhibitor
3. Indirect thromboin inhibitors, Direct thromboin inhibitors , Ancorod
4. Renal impairment
5. Less bleeding than Warfarin
6. Stimulate conversion of fibrinogen to abnormal fibrin which is then broken
7. preventing postoperative various thrombosis and pulmonary embolism
8. Vit K
9. Transient alopecia and Osteoporosis
10. Tetracycline and ……………….

MCQ

1. Both
2. Apixaban
3. Dabigatran
4. Tinzaparin
5. Fondaparinux
6. All
7. Ancorod
8. Warfarin
9. Heparin
10. Rifampicin
11. Heparin
12. Heparin

True and False

1. False
2. False
3. True
4. True
5. False.
6. False
7. False
8. True
9. False
10. False
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