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L10, Salicylates, toxicology

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MCQ

1-uses of Salicylate.

 a. antipyretic. 

b. Antipyretic
c. Anti inflammatory
d. a&b
E. all of The above

2-half life at Theraputic concentration.... but of Toxic....
a. 20 hours, 4 hours
b. 20h,2h
c.2-4h, >20h

3-Elimination of Salicylate by.....
a.liver
b. kidney
c. Gall bladder

4-Mechanism of Action of salicylate ....
a-inhibition of PG
b. Inhibition of Neutrophils.
c.both


5- earlist manfistation of Salicylate Toxicity is...

a. Tinnitus
b. Nausea & vomiting
C. CNS. Stimulation. 


6-one of metabolic disturbance of Salicylate Toxicity is

a. hypoglycemia
b. hypothermia
C.hypervolemia
d.all of The above

7-which of The Flowing are salicylate Toxidrome?

a. Tinnitus
b. Git irritation
c. hyperventilation
d. all of Theat

T or F


1- In Acute Toxicity in children<4 years There is Respiratory Alkalosis

2-Methyl Salicylate is less potent Than ASA

3-90%of Salicylate metabolise in Liver

4-In Salicylate Toxicity There is CNS stimulation only

5- urine Alkalinzation is the best Treatment if plasma Salicylate >100mg

6-Hemodialysis is used if plasma Salicylate >60mg in chronic toxicity.




MCQ Answers

1-e

2-c

3-b

4-c

5-b

6-a

7-d 

T or F answers

1-F

2-F

3-T

4-F

5-F

6-T




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