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L15, toxic alcohol , Toxicology

Ethanol 

Lecture video part 1 

Part 1 Data 

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Toxic alcohol 

Lecture video part 2


Part 2 Data

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Mcq



1-McEwen sign is present in massive intake of: 

A-Barbiturate 
B-Ethanol 
C-Atropine 
D-Imipramine 

2-Slurred speech is present in acute poisoning of: 

A-Atropine
B-Ethanol 
C-Cannabis 
D-Imipramine 

3-In ethanol withdrawal, the following are present except: 

A-Auditory hallucination 
B-Tachycardia 
C-Constricted pupil 
D-Fever and sweating 

4-Antidote for methyl alcohol is: 
DMSA 

A-BAL 
B-EDTA 
C-Ethyl alcohol 

5-Green tongue syndrome occurs with: 

A-Ethanol 
B-Methanol 
C-Ethylene glycol 
D-All of the above 

6-The target organ of methanol is

A-Kidney 
B-Liver 
C-Optic nerve
D-Heart

7-Which one of the following has toxicity on optic nerve? 

A-Ethanol 
B-Methanol 
C-Ethylene glycol 
D-Isopropyl 
E-Propylene glycol 

8-Which one of the following is a toxic metabolite for methanol? 

A-Acetic acid 
B-Formic acid 
C-Folic acid 
D-NAPQI 
E-Acetaldehyde 

9-Which one of the following is used as antidote for methanol toxicity? 

A-Flumazenil 
B-Fomepizole 
C-Antabuse 
D-NAC 
E-Atropine

10-Hemodialysis is indicated in methanol toxicity in case of: 

A-Methanol level is less than 5 mg/l00ml 
B-Format is less than 5mg/100mI 
C-Acidosis responsive to bicarbonate 
D-Visual impairment 
E-Severe nausea, vomiting and abdominal pain

11-As regard methanol toxicity, which of the following statement is wrong: 

A-Illicit alcohol production remains a global source of methanol poisoning. 
B-The accumulation of formic acid is associated with the onset of clinical symptoms 
C-Crystalluria is one of toxic features of poisoning. 
D-Abnormal fundus examination present. 

12-With regard to the alcohols which is false? 

A-Methanol causes snow storm vision in severe intoxication 
B-Ingestion of both methanol and ethylene glycol causes a metabolic acidosis with an increased anion gap. 
C-Neither methanol Nor ethylene glycol are absorbed through the skin, 
D-You might expect to find oxalate crystals in the urine of a patient who had an ethylene glycol overdose. 

13-One of the following statements is false about blindness due to methanol poisoning

A-Due to direct effect of formic acid. 
B-Fomipezole, a specific alcohol dehydrogenase inhibitor is helpful. 
C-Ethanol is helpful to prevent blindness. 
D-Gastric lavage is not helpful. 

14-Visual disturbance due to methanol toxicity include the following signs except:

A-Diplopia and photophobia 
B-Nystagmus and hyperemia of optic disc 
C-Retinal edema and optic atrophy 
D-Blurred vision and reactive dilated pupils 


15-In methyl alcohol poisoning optic papillitis and retinal edema are occurred due to: 

A-Formic acid production in the retina 
B-Formaldehyde production in the retina 
C-Acetaldehyde production in the retina 
D-Acetic acid production in the retina 

16-Ingestion of ethylene glycol induces nephrotoxicity within 

A-12-24 hours 
B-24-72 hours 
C-3-6 days 
D-6- 12 days

17-Which of the following does not represent a manifestation of ethylene glycol poisoning? 

A-Nystagmus 
B-Abnormal optic fundus 
C-Tachycardia and tachypnea 
D-Sever hypotension
 
18-In diagnosis of ethylene glycol toxicity, the laboratory results include all the following except: 

A-Leukocytosis 
B-Hypocalcemia 
C-Hypercalcemia 
D-Serum ethylene glycol greater than 20mg/dL

Answers 

1-B
2-B
3-C
4-D
5-B
6-C
7-B
8-B
9-B
10-D
11-C
12-C
13-A
14-D
15-B
16-B
17-B
18-C





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