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L6, acetaminophen toxicity, toxicology

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MCQ 

the loading and maintenance dose of oral NAC (200mg sachets) for patient with APAP toxicity, weighing 80 kg are:

 A-60 then 30 sachets 
 B-50 then 20 sachets 
 C-56 then 28 sachets 
 D-20 then 12 sachets

2-A mentally retarded adult patient came to Benha PCC at 8 pm with history given by his relevant of 2 successive oral toxic doses of acetaminophen, the 1st one (20 tablets), was at 4 pm and the 2nd dose (30 tablets), was at 7 pm. what are the correct treatment procedure(s)?


 A-oral NAC therapy 
 B-oral activated charcoal 
 C-activated charcoal then oral NAC 
 D-activated charcoal and IV NAC simultaneously


3-An adult woman,70 kg, had commited suicidal attempt by swallowing one strip (10 tab) of acetaminophen 1 hour ago, she came to the ER . Best management in this case:


 A-Activared charcoal 
 B- Oral NAC

C-Gastric lavage 
 D- No ttt needed


4-The 4 hours treatment line for APAP toxicity in diabetic adult patient treated by insulin is:


A200 mg/dl 
 B- 150 mg/dl
C- than 200 mg/dl.      
 D- less than 150 mg/dl



5)- All are true with N-acetylcystiene (NAC) except


a) Is effective in preventing the development of hepatotoxicity of

b) Diminishes hepatic necrosis in late acetaminophen toxicity acetaminophen

c) Has one SH group and its action is similar to BAL



Answers


 


1-C

2-D

3-A

4-B

5-C



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