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L12, Cholinergic pharmacology 2( Parasympathomimetics), Pharmacology

 Lecture video 

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MCQ 

                                                    

1-Parasympathomymetic Actions in stimulation of MR are?

a-decrease HR and C. O. P

b-decrease blood preasure

c-VD of blood vessels

d-all of the above

2-Acetylcholine cause blood vessels VD through producing of?

 a-carbon monoxide

b-carbonic acid

C-Nitric oxide

3-Actions of parasympathomymetic on eye include all of the following except?

a-stimulate ciliary muscle contraction for near vision

b-stimulate tears

c-increase IOP

d-causing mydrayasis

e-c,d

4-Effects of parasympathomymetics on GIT include
a-increase salivary secretions
b-increase gastric secretions

C-decrease intestinal secretions and mobility
d-all of the above
e-all except C

5-Adverse effects of parasympathomymetics(Acetylcholine) iinclude

a-bradycardia and hypotension

b-myosis

c-bronchospasm

d-all of the above

6-Contraindications of parasympathomymetics include

a-bradycardia

b-bronchial asthma

d-physiological (functional) obstruction of urinary bladder and GIT

e-all of the above

f-all except d

7-All drugs act on M and N receptors except

a-carbachol

b-phesostigmine

c-neostigimine

d-bethanicol

-8 which of the following drugs absorbed partial?

a-carbachol

b-bethanichol

c-a, b

d-methanichol

9-bethanichol acts mainly on

a-eye

b-heart

c-GIT and urinary bladder

10-which of the following drugs used post operative?

a-Neostigmine

b-carbachol

c-bethanichol

d-all of the above

11-Drug of choice in glaucoma emergency

a-neostigmine

b-pilocarpine

c-bethanicol


12-Which of the following is reversible anti choline estrase?
a-physostigmine
b-neostigmine

c-metrifonate

d-edrophonium
e-all except C

13-which of the following is antidote to curare toxicity?

a-bethanichol

b-carbachol

c-neostigimine

d-phesostigmine 


14-which of the following is antidote to Atropine?
a-malathion
b-parathion
c-phesostigmine
d-bethanichol

e-A, B only


15-which of the following not absorbed orally?

a-bethanichol

b-carbachol

c-a, b

d-Acetyl choline


16-which drug is destructed by True Ch. E only?

a-phesostigmine


b-bethanichol

c-Acetylcholine

d-methacholine


17-which drug is absorbed completely?

a-bethanichol

b-A. Ch

c-carbachol
d-a, c

18-which drug acts mainly on heart?

a-methacholine

b-bethanichol

c-a, b

19-which drug has short duration?

a-phesostigmine

b-neostigmine

c-edrophonium

d-all of the above


 20-which drug is used in TTT of Alzeheimer?

a-carbachol

b-neostigmine

C-phesostigmine


 21-Which drug acts on MR only?

a-bethanichol

b-carbachol

c-methanichol

d-A, B

,e-A C            

Answers mcQ 

1-d

2-c

3-e

4-e

5-d

6-f

7-d

8-d

9-c

10-d

11-b

12-e

13-c

14-c

15-d

16-d

17-d

18-a

19-d

20-c

21-e





                           True and False 


1-A.Ch cause VD in blood vessels by direct mechanism


2-Acetylcholine decrease HR and Increase C. O. P


3-A.Ch causes bronchoconstrictuon


4-Duration of methacholine in circulation is equel to carbchol


5-Direct parasympathomymetics act by inhibiting choline esterase


6-pilocarbine and phesostigmine are tertiary amine


7-pilocarbine is the drug of choice in glaucoma emergency


8-Acetylcholine can be absorbed orally


9-Parkinsonism and peptic ulcer are Contraindications of parasympathomymetics


10-Antidote of Atropine is neostigmine but antidote of curare is phesostigmine


                                       Answers T&F


1 – false

2-false

3-True

4-false

5-false

6-True

7-true

8-false

9-true

10-false


Short essay


1-mention Actions of parasympathomymetics related to MR stimulation

2-mention Cholinergic agents adverse effects

3-what are Contraindications of parasympathomymetics?

4-Mention 3 examples of direct Parasympathomimetics

5-mention 3 examples of reversible anti choline estrase drugs


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